What are Inherited Cardiovascular Conditions?

Inherited Cardiovascular Conditions (or ICCs) are a group of different genetic conditions that mainly affect the heart or main blood vessels.

There are 4 main groups of conditions:

Cardiomyopathies – these conditions mainly affect the muscle of the heart.

Examples include:

  • Hypertrophic cardiomyopathy - when the heart muscle becomes too thick
  • Dilated cardiomyopathy - when the heart enlarges and the muscle becomes weak
  • Arrhythmogenic cardiomyopathy - when the muscle of the heart is replaced by fat and scar

Ion channel disorders – these conditions mainly affect the electrical system of the heart. These electrical anomalies are associated with deaths due sudden arrhythmic death syndrome (SADS), where the heart structure in the affected individual is normal. Examples include:

  • Long QT syndrome – when the heart takes too long to relax
  • Brugada syndrome – an unusual condition with a characteristic pattern on the heart trace
  • Catecholaminergic polymorphic VT – a rare condition that causes heart rhythm problems during times of stress or exercise

Neuromuscular conditions – these conditions affect both the muscles of the body and the muscle or electrical system of the heart.

  • Muscular dystrophy – conditions such as Duchenne and Becker's muscular dystrophy can cause significant weakness of the muscles of the body and can also cause heart failure
  • Myotonic dystrophy – this is a condition in which the muscles of the body get tired easily and it can also affect the heart electrical system

Conditions affecting the major blood vessels – these conditions affect the major blood vessels.

  • Marfan syndrome – a condition that affects many different aspects of the body including the eyes, the joints, the heart and the main artery called the aorta.
  • Ehler's Danlos syndrome – a condition that affects the skin and joints and the main artery (aorta).

Partners & Supporters

  • Gateley
    Pukaar News
    British Heart Foundation
    Westleigh Developments
  • Sileby Town CC
    Kasabian
    Leicester Mercury
    Trophy Parlour
  • Rothley Parish Council
    Gleeds
    Cipher Entertainment
    Willmott Dixon
  • Barwood
    Leicester Coritanian
    Demon Media
    Sports Cardiology UK
  • Shepshed Lions Club - Community First Responders
    UHL Trust
    Rawlins
    AFC Andrews
  • Leicester Legends
    Leicestershire County Council
    Health For Teens
    UK Paintball
  • Musical Village
    Gem 106
    Quorn Football Club
    YHW
  • Arrhythmia Alliance
    Leicester Unity Boxing Club
    Agora
    Bradgate Park Trust
  • De Lisle
    Leicester City In the Community
    BBC
    Loughborough Town Cricket Club
  • Warriors Basketball Club
    Shepshed Lions - Community First Responders
    LRSport
    David Wilson Homes
  • Leicestershire and Rutland County FA
    6PM
    Samworth Brothers
    Boden
  • Inside Land
    Leicester Tigers
    Leicester City FC Community Trust
    Dickinson & Morris
  • BBC Radio Leicester
    Leicester City Council
    De Montfort Students Union
    CKI Martial Arts
  • Jersey Budd
    Jessica Michelle School of Dance
    Rothley Park Cricket Club
    East Midlands Ambulance Service
  • Oak FM
    ITV Central
    Loughborough Echo
    Soar Media
  • Heartwize
    Longslade Community College